Gene

syn2a

ID
ZDB-GENE-040718-341
Name
synapsin IIa
Symbol
syn2a Nomenclature History
Previous Names
  • syn2
  • zgc:92311
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have ATP binding activity. Predicted to be involved in neurotransmitter secretion. Predicted to localize to synaptic vesicle membrane. Is expressed in DEL; nervous system; spinal cord neural tube; and yolk syncytial layer. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SYN2 (synapsin II).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from Garbarino et al., 2014
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With syn2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
schizophrenia Alliance {Schizophrenia, susceptibility to} 181500
Associated With syn2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR020897 Synapsin, pre-ATP-grasp domain
Domain IPR020898 Synapsin, ATP-binding domain
Family IPR001359 Synapsin
Family IPR028712 Synapsin-2/3
Homologous_superfamily IPR013815 ATP-grasp fold, subdomain 1
Homologous_superfamily IPR016185 Pre-ATP-grasp domain superfamily
PTM IPR019736 Synapsin, phosphorylation site
Domain Details Per Protein
Protein Length ATP-grasp fold, subdomain 1 Pre-ATP-grasp domain superfamily Synapsin Synapsin-2/3 Synapsin, ATP-binding domain Synapsin, phosphorylation site Synapsin, pre-ATP-grasp domain
UniProtKB:F1R0A8 463
UniProtKB:Q6DHH6 463
UniProtKB:Q5CD49 252
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations