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ZIRC
ZFIN ID: ZDB-GENE-040718-327
Gene Name: lens intrinsic membrane protein 2.3
Gene Symbol: lim2.3    Nomenclature History

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Attributions

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Previous Names: mp19-3 (1), zgc:92719

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to be a structural constituent of eye lens. Predicted to localize to the plasma membrane. Human ortholog(s) of this gene implicated in cataract and cataract 19 multiple types. Is expressed in lens and solid lens vesicle. Orthologous to human LIM2 (lens intrinsic membrane protein 2).
Genome Resources: Alliance (1),  Gene:436860 (1),  Ensembl(GRCz11):ENSDARG00000037402 (1)
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [MGC:92719]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35861 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lim2.3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    cataract 19 multiple types Alliance Cataract 19, multiple types 615277
    DISEASE ASSOCIATED WITH lim2.3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    Molecular Function structural constituent of eye lens (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lim2.3-201 (1)    Ensembl 772
    lim2.3-202 (1)    Ensembl 722
    ncRNA lim2.3-002 (1)    Ensembl 426
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lim2.3 No data available
    MARKER RELATIONSHIPS
    lim2.3 Contained in: [BAC] DKEY-4P15 (1) (order this)
    lim2.3 Encodes: [cDNA] MGC:92719 (1) (order this), MGC:113905 (1) (order this), MGC:192981 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002587 (1) 781 bp
    Genomic GenBank:CR626889 (1) 205513 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q6DGY5 (1) 172 aa
    Sequence Clusters UniGene:88734 (1)
    Sequence Information (all 18)
    ORTHOLOGY for lim2.3 ( Chr: 15 )
    CITATIONS (19)