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ZIRC
ZFIN ID: ZDB-GENE-040718-310
Gene Name: aquaporin 12
Gene Symbol: aqp12    Nomenclature History

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Previous Names: wu:fb60e09 (1), zgc:152755, zgc:92747 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have channel activity. Involved in cellular response to estrogen stimulus. Predicted to localize to the cytoplasm. Is expressed in several structures, including eye; gill; integument; liver; and pleuroperitoneal region. Orthologous to several human genes including AQP12B (aquaporin 12B).
Genome Resources: Alliance (1),  Gene:436844 (1),  Ensembl(GRCz11):ENSDARG00000043279 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32367 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH aqp12 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH aqp12 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to estrogen stimulus (more)
    Cellular Component integral component of membrane (more)
    Molecular Function channel activity (more)
    GO Terms (all 6)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA aqp12-201 (1)    Ensembl 994
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aqp12 No data available
    MARKER RELATIONSHIPS
    aqp12 Contained in: [BAC] DKEY-20I20 (1) (order this)
    aqp12 Contains: [SNP] rs3729158 (1)
    aqp12 Encodes: [EST] fb60e09
    [cDNA] MGC:92747 (1) (order this), MGC:152755 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045862 (1) 970 bp
    Genomic GenBank:BX324210 (1) 230738 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q502T6 (1) 283 aa
    Sequence Clusters UniGene:77221 (1)
    Sequence Information (all 20)
    ORTHOLOGY for aqp12 ( Chr: 22 )
    CITATIONS (25)