ZFIN ID: ZDB-GENE-040718-310
Gene Name: aquaporin 12
Gene Symbol: aqp12    Nomenclature History

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Previous Names: wu:fb60e09 (1), zgc:152755, zgc:92747 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have channel activity. Involved in cellular response to estrogen stimulus. Predicted to localize to cytoplasm. Is expressed in several structures, including eye; gill; integument; liver; and pleuroperitoneal region. Orthologous to human AQP12A (aquaporin 12A) and AQP12B (aquaporin 12B).
Genome Resources: Alliance (1),  Gene:436844 (1),  Ensembl(GRCz11):ENSDARG00000043279 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32367 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH aqp12 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH aqp12 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to estrogen stimulus (more)
    Cellular Component integral component of membrane (more)
    Molecular Function channel activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA aqp12-201 (1)    Ensembl 994
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aqp12 No data available
    MARKER RELATIONSHIPS
    aqp12 Contained in: [BAC] DKEY-20I20 (1) (order this)
    aqp12 Contains: [SNP] rs3729158 (1)
    aqp12 Encodes: [EST] fb60e09
    [cDNA] MGC:92747 (1), MGC:152755
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045862 (1) 970 nt
    Genomic GenBank:BX324210 (1) 230738 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q502T6 (1) 283 aa
    Sequence Information (all 19)
    ORTHOLOGY for aqp12 ( Chr: 22 )
    CITATIONS (27)