ZFIN ID: ZDB-GENE-040718-291
Gene Name: polymerase (RNA) III (DNA directed) polypeptide K
Gene Symbol: polr3k    Nomenclature History

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Previous Name: zgc:92774

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have DNA-directed 5'-3' RNA polymerase activity; nucleic acid binding activity; and zinc ion binding activity. Involved in hematopoietic stem cell homeostasis. Predicted to localize to RNA polymerase III complex. Is expressed in hematopoietic system. Orthologous to human POLR3K (RNA polymerase III subunit K).
Genome Resources: Alliance (1),  Gene:436826 (1),  Ensembl(GRCz11):ENSDARG00000037835 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92774]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa40148 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-polr3k N/A 2
    DISEASE ASSOCIATED WITH polr3k HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH polr3k VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hematopoietic stem cell homeostasis (more)
    Cellular Component nucleolus (more)
    Molecular Function DNA-directed 5'-3' RNA polymerase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA polr3k-201 (1)    Ensembl 690
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM polr3k No data available
    MARKER RELATIONSHIPS
    polr3k Contained in: [BAC] CH73-103D11 (1)
    polr3k Encodes: [cDNA] MGC:92774 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002553 (1) 698 nt
    Genomic GenBank:CU463855 (1) 39267 nt
    Select Tool
    Polypeptide UniProtKB:Q6DGU0 (1) 108 aa
    Sequence Information (all 9)
    ORTHOLOGY for polr3k ( Chr: 3 )
    CITATIONS (23)