Gene

pnpla3

ID
ZDB-GENE-040718-27
Name
patatin-like phospholipase domain containing 3
Symbol
pnpla3 Nomenclature History
Previous Names
  • zgc:92195
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have triglyceride lipase activity. Involved in liver development. Predicted to localize to cytoplasm; lipid droplet; and membrane. Human ortholog(s) of this gene implicated in coronary artery disease; fatty liver disease (multiple); liver disease (multiple); and type 2 diabetes mellitus. Orthologous to human PNPLA3 (patatin like phospholipase domain containing 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pnpla3 Human Ortholog
No data available
Associated With pnpla3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002641 Patatin-like phospholipase domain
Domain IPR033903 Patatin-like phospholipase domain-containing protein 2
Family IPR033562 Patatin-like phospholipase domain-containing protein
Homologous_superfamily IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase
Domain Details Per Protein
Protein Length Acyl transferase/acyl hydrolase/lysophospholipase Patatin-like phospholipase domain Patatin-like phospholipase domain-containing protein Patatin-like phospholipase domain-containing protein 2
UniProtKB:Q6DHN9 473
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations