ZFIN ID: ZDB-GENE-040718-264
Gene Name: regulator of G protein signaling 8
Gene Symbol: rgs8    Nomenclature History

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Previous Name: zgc:92913 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity. Predicted to be involved in G protein-coupled acetylcholine receptor signaling pathway and regulation of dopamine receptor signaling pathway. Predicted to localize to several cellular components, including dendrite; extrinsic component of cytoplasmic side of plasma membrane; and neuronal cell body membrane. Is expressed in forebrain and retina. Orthologous to human RGS8 (regulator of G protein signaling 8).
Genome Resources: Alliance (1),  Gene:436804 (1),  Ensembl(GRCz11):ENSDARG00000070037 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa25342 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH rgs8 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH rgs8 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process G protein-coupled acetylcholine receptor signaling pathway (more)
Cellular Component dendrite (more)
Molecular Function GTPase activator activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rgs8-201 (1)    Ensembl 1467
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM rgs8 No data available
MARKER RELATIONSHIPS
rgs8 Contained in: [BAC] DKEY-39O12 (1) (order this)
rgs8 Encodes: [cDNA] MGC:92913 (1), MGC:192978 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001002531 (1) 1402 nt
Genomic GenBank:CR854912 (1) 170067 nt
Select Tool
Polypeptide UniProtKB:B2GTH3 (1) 174 aa
Sequence Information (all 15)
ORTHOLOGY for rgs8 ( Chr: 6 )
CITATIONS (20)