Gene

rel

ID
ZDB-GENE-040718-255
Name
v-rel avian reticuloendotheliosis viral oncogene homolog
Symbol
rel Nomenclature History
Previous Names
  • c-rel (1)
  • zgc:100833 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Exhibits protein heterodimerization activity. Involved in brain development. Predicted to localize to cytosol and nucleoplasm. Is expressed in intestine. Orthologous to human REL (REL proto-oncogene, NF-kB subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Bagheri et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rel Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Immunodeficiency 92 619652
Associated With rel Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR030492 Rel homology domain, conserved site
Domain IPR002909 IPT domain
Domain IPR011539 Rel homology domain, DNA-binding domain
Domain IPR032397 Rel homology dimerisation domain
Domain IPR033926 NFkappaB IPT domain
Domain IPR042845 Proto-oncogene c-Rel, RHD, N-terminal subdomain
Family IPR000451 NF-kappa-B/Dorsal
Homologous_superfamily IPR008967 p53-like transcription factor, DNA-binding domain superfamily
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR014756 Immunoglobulin E-set
Homologous_superfamily IPR037059 Rel homology domain (RHD), DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin E-set Immunoglobulin-like fold IPT domain NF-kappa-B/Dorsal NFkappaB IPT domain p53-like transcription factor, DNA-binding domain superfamily Proto-oncogene c-Rel, RHD, N-terminal subdomain Rel homology dimerisation domain Rel homology domain, conserved site Rel homology domain, DNA-binding domain Rel homology domain (RHD), DNA-binding domain superfamily
UniProtKB:Q6DGE6 596
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA rel-201 (1) Havana 2137 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations