ZFIN ID: ZDB-GENE-040718-247
Gene Name: ubiquitin-conjugating enzyme E2B (RAD6 homolog)
Gene Symbol: ube2b    Nomenclature History

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Previous Name: zgc:100921

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have ubiquitin conjugating enzyme activity. Predicted to be involved in DNA repair; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to localize to HULC complex and nuclear chromatin. Orthologous to human UBE2B (ubiquitin conjugating enzyme E2 B).
Genome Resources: Alliance (1),  Gene:437020 (1),  Ensembl(GRCz11):ENSDARG00000026035 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37385 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ube2b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ube2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ube2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process DNA repair (more)
    Cellular Component HULC complex (more)
    Molecular Function ATP binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ube2b-201 (1)    Ensembl 2065
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ube2b No data available
    MARKER RELATIONSHIPS
    ube2b Contained in: [BAC] CH73-202G8 (1)
    ube2b Encodes: [cDNA] MGC:100921 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002747 (1) 2065 nt
    Genomic GenBank:FP017197 (1) 101814 nt
    Select Tool
    Polypeptide UniProtKB:Q6DGE1 (1) 152 aa
    Sequence Information (all 9)
    ORTHOLOGY for ube2b ( Chr: 21 )
    CITATIONS (18)