ZFIN ID: ZDB-GENE-040718-233
Gene Name: lactase-like a
Gene Symbol: lctla    Nomenclature History

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Previous Name: zgc:101102

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have beta-glucosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to localize to endoplasmic reticulum. Is expressed in lens. Orthologous to human LCTL (lactase like).
Genome Resources: Alliance (1),  Gene:437008 (1),  Ensembl(GRCz11):ENSDARG00000036139 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7161349]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa543 Point Mutation Unknown Premature Stop ENU
sa20996 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lctla HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lctla VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process carbohydrate metabolic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function hydrolase activity, hydrolyzing O-glycosyl compounds (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lctla-201 (1)    Ensembl 2293
    lctla-202 (1)    Ensembl 1285
    lctla-203 (1)    Ensembl 996
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lctla No data available
    MARKER RELATIONSHIPS
    lctla Contained in: [BAC] CH211-98N17 (1)
    lctla Encodes: [EST] IMAGE:7161349 (1)
    [cDNA] MGC:101102 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002735 (1) 2321 nt
    Genomic GenBank:CR388195 193210 nt
    Select Tool
    Polypeptide UniProtKB:Q6DGC8 (1) 552 aa
    Sequence Information (all 20)
    ORTHOLOGY for lctla ( Chr: 7 )
    CITATIONS (19)