Gene

kpna2

ID
ZDB-GENE-040718-22
Name
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
Symbol
kpna2 Nomenclature History
Previous Names
  • hm:zeh0389
  • hm:zeh0389r
  • zeh0389
  • zeh0389r
  • zgc:113902
  • zgc:86945 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to localize to cytosol; nuclear pore; and nucleoplasm. Is expressed in proliferative region. Orthologous to human KPNA2 (karyopherin subunit alpha 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kpna2 Human Ortholog
No data available
Associated With kpna2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002652 Importin-alpha, importin-beta-binding domain
Family IPR024931 Importin subunit alpha
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR036975 Importin-alpha, importin-beta-binding domain superfamily
Repeat IPR000225 Armadillo
Repeat IPR032413 Atypical Arm repeat
Domain Details Per Protein
Protein Length Armadillo Armadillo-like helical Armadillo-type fold Atypical Arm repeat Importin-alpha, importin-beta-binding domain Importin-alpha, importin-beta-binding domain superfamily Importin subunit alpha
UniProtKB:F1QG82 525
UniProtKB:Q6DI01 525
UniProtKB:Q498Q1 127
UniProtKB:A4VAL1 124
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations