ZFIN ID: ZDB-GENE-040718-184
Gene Name: glutathione S-transferase zeta 1
Gene Symbol: gstz1    Nomenclature History

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Previous Names: zgc:113898, zgc:92869

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Exhibits glutathione transferase activity. Predicted to be involved in L-phenylalanine catabolic process and glutathione metabolic process. Predicted to localize to the mitochondrion. Is expressed in brain; gill; liver; and pleuroperitoneal region. Orthologous to human GSTZ1 (glutathione S-transferase zeta 1).
Genome Resources: Alliance (1),  Gene:436754 (1),  Ensembl(GRCz11):ENSDARG00000027984 (2)
GENE EXPRESSION
All Expression Data: 10 figures from 3 publications
Directly Submitted Expression Data: 7 figures (2 images) from Thisse et al., 2004 [MGC:113898]
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa42995 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42996 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gstz1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    [Maleylacetoacetate isomerase deficiency] 617596
    DISEASE ASSOCIATED WITH gstz1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process aromatic amino acid family metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function glutathione transferase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR004045 Glutathione S-transferase, N-terminal
    Domain IPR004046 Glutathione S-transferase, C-terminal
    Family IPR005955 Glutathione S-transferases, class Zeta
    Domain IPR010987 Glutathione S-transferase, C-terminal-like
    Domain IPR034330 Glutathione S-transferases, class Zeta , C-terminal
    Domain IPR034333 Glutathione S-transferases, class Zeta , N-terminal
    Homologous_superfamily IPR036249 Thioredoxin-like superfamily
    Homologous_superfamily IPR036282 Glutathione S-transferase, C-terminal domain superfamily
    Family IPR040079 Glutathione Transferase family
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gstz1-001 (1) 1058
    gstz1-002 (1) 798
    gstz1-004 (1) 796
    gstz1-202 (1)    Ensembl 766
    gstz1-203 (1)    Ensembl 723
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gstz1 No data available
    MARKER RELATIONSHIPS
    gstz1 Contained in: [Fosmid] ZFOS-810H6 (1)
    gstz1 Encodes: [cDNA] MGC:92869 (1), MGC:113898 (1), MGC:191161 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030271 (1) 1109 bp
    Genomic GenBank:CU694272 (1) 38971 bp
    Select Tool
    Polypeptide UniProtKB:Q6DGL3 (1) 220 aa
    Sequence Information (all 27)
    ORTHOLOGY for gstz1 ( Chr: 17 )
    CITATIONS (21)