ZFIN ID: ZDB-GENE-040718-176
Gene Name: lactate dehydrogenase Bb
Gene Symbol: ldhbb    Nomenclature History

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Previous Name: zgc:92882 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have L-lactate dehydrogenase activity. Predicted to be involved in carbohydrate metabolic process; carboxylic acid metabolic process; and oxidation-reduction process. Predicted to localize to cytoplasm. Is expressed in liver and retinal photoreceptor layer. Orthologous to human LDHB (lactate dehydrogenase B).
Genome Resources: Alliance (1),  Gene:436747 (1),  Ensembl(GRCz11):ENSDARG00000071076 (2)
GENE EXPRESSION
All Expression Data: 9 figures from 2 publications
Directly Submitted Expression Data: 7 figures (5 images) from Thisse et al., 2004 [MGC:92882]
Wild-type Stages, Structures: Pharyngula:High-pec (42.0h-48.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa44214 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ldhbb HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    [Lactate dehydrogenase-B deficiency] 614128
    DISEASE ASSOCIATED WITH ldhbb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process carbohydrate metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ldhbb-201 (1)    Ensembl 1636
    ldhbb-202 (1)    Ensembl 517
    ldhbb-203 (1)    Ensembl 923
    ncRNA ldhbb-004 (1)    Ensembl 561
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ldhbb No data available
    MARKER RELATIONSHIPS
    ldhbb Contained in: [BAC] CH211-267N3 (1)
    ldhbb Encodes: [cDNA] MGC:92882 (1), MGC:192374 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002474 (1) 1618 nt
    Genomic GenBank:CR855322 (1) 140318 nt
    Select Tool
    Polypeptide UniProtKB:B2GRW6 (1) 334 aa
    Sequence Information (all 23)
    ORTHOLOGY for ldhbb ( Chr: 25 )
    CITATIONS (28)