ZFIN ID: ZDB-GENE-040718-160
Gene Name: complexin 2, like
Gene Symbol: cplx2l    Nomenclature History

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Previous Names: cplx2, fc97e10, wu:fc97e10 (1), wu:fq40b06 (1), zgc:92325

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have syntaxin-1 binding activity. Predicted to be involved in regulation of neurotransmitter secretion and synaptic vesicle exocytosis. Predicted to localize to SNARE complex and terminal bouton. Is expressed in nervous system; neurons; and retina. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 63. Orthologous to human CPLX1 (complexin 1).
Genome Resources: Alliance (1),  Gene:436732 (1),  Ensembl(GRCz11):ENSDARG00000018997 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 4 figures (16 images) from Rauch et al., 2003 [fq40b06]
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zko268a Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko268b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cplx2l 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cplx2l HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cplx2l VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neurotransmitter transport (more)
    Cellular Component SNARE complex (more)
    Molecular Function syntaxin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cplx2l-201 (1)    Ensembl 1524
    cplx2l-202 (1)    Ensembl 1610
    cplx2l-203 (1)    Ensembl 1632
    cplx2l-204 (1)    Ensembl 1846
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cplx2l No data available
    MARKER RELATIONSHIPS
    cplx2l Contained in: [BAC] CH211-288H2 (1)
    cplx2l Contains: [SNP] rs3727498 (1), rs3727499 (1), rs3727500 (1), rs3727501 (1)
    cplx2l Encodes: [EST] fc97e10, fq40b06 (1) (order this)
    [cDNA] MGC:92325 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002459 (1) 1550 nt
    Genomic GenBank:CR388406 (1) 161800 nt
    Select Tool
    Polypeptide UniProtKB:Q6DHG4 (1) 133 aa
    Sequence Information (all 14)
    ORTHOLOGY for cplx2l ( Chr: 1 )
    CITATIONS (21)