ZFIN ID: ZDB-GENE-040715-3
Gene Name: cortactin
Gene Symbol: cttn    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Predicted to be involved in generation of neurons; postsynaptic actin cytoskeleton organization; and regulation of actin filament polymerization. Predicted to colocalize with actin filament and voltage-gated potassium channel complex. Orthologous to human CTTN (cortactin).
Genome Resources: Alliance (1),  Gene:445561 (1),  Ensembl(GRCz11):ENSDARG00000011777 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17004 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23395 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cttn HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cttn VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament polymerization (more)
    Cellular Component COLOCALIZES_WITH   actin filament (more)
    Molecular Function actin filament binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cttn-001 (1) 2451
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cttn No data available
    MARKER RELATIONSHIPS
    cttn Encodes: [cDNA] MGC:193827 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004121 (1) 1838 nt
    Polypeptide UniProtKB:F1Q932 (1) 536 aa
    Sequence Information (all 15)
    ORTHOLOGY for cttn ( Chr: 18 )
    CITATIONS (20)