Gene

twf1b

ID
ZDB-GENE-040711-3
Name
twinfilin actin-binding protein 1b
Symbol
twf1b Nomenclature History
Previous Names
  • zgc:92472
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Is predicted to enable actin filament binding activity and actin monomer binding activity. Involved in actin filament depolymerization; negative regulation of actin filament polymerization; and regulation of plasma membrane bounded cell projection organization. Acts upstream of or within negative regulation of actin filament polymerization. Predicted to be located in cytoskeleton. Is expressed in gut and nervous system. Orthologous to human TWF1 (twinfilin actin binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With twf1b Human Ortholog
No data available
Associated With twf1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002108 Actin-depolymerising factor homology domain
Family IPR028458 Twinfilin
Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
Domain Details Per Protein
Protein Length Actin-depolymerising factor homology domain ADF-H/Gelsolin-like domain superfamily Twinfilin
UniProtKB:Q6DKF4 349
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations