header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040704-28
Gene Name: cytochrome P450, family 2, subfamily X, polypeptide 8
Gene Symbol: cyp2x8    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: zgc:192870, zgc:91876

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in acute myeloid leukemia; asthma; autoimmune hepatitis; precursor lymphoblastic lymphoma/leukemia; and rhinitis. Orthologous to human CYP2D6 (cytochrome P450 family 2 subfamily D member 6).
Genome Resources: Alliance (1),  Gene:431734 (1),  Ensembl(GRCz11):ENSDARG00000043997 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014677Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023175Tg Transgenic Insertion Unknown Unknown DNA
    la023177Tg Transgenic Insertion Unknown Unknown DNA
    la023178Tg Transgenic Insertion Unknown Unknown DNA
    la028678Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13071 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13766 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30750 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cyp2x8 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cyp2x8 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cytoplasm (more)
    Molecular Function heme binding (more)
    GO Terms (all 14)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cyp2x8-201 (1)    Ensembl 1575
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp2x8 No data available
    MARKER RELATIONSHIPS
    cyp2x8 Contained in: [BAC] DKEY-217G8 (1) (order this)
    cyp2x8 Encodes: [cDNA] MGC:91876 (1) (order this), MGC:192870 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002187 (1) 1480 bp
    Genomic GenBank:CU468035 (1) 225398 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8QED6 (1) 491 aa
    Sequence Clusters UniGene:134435 (1)
    Sequence Information (all 16)
    ORTHOLOGY for cyp2x8 ( Chr: 25 )
    CITATIONS (21)