ZFIN ID: ZDB-GENE-040704-27
Gene Name: enolase 2
Gene Symbol: eno2    Nomenclature History

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Previous Names: eno3 (1), fc09h05, wu:fc09h05, zgc:92418 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have phosphopyruvate hydratase activity. Predicted to be involved in glycolytic process and regulation of vacuole fusion, non-autophagic. Predicted to localize to phosphopyruvate hydratase complex. Is expressed in musculature system; nervous system; neural tube; presumptive neural retina; and trigeminal placode. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human ENO2 (enolase 2).
Genome Resources: Alliance (1),  Gene:402874 (1),  Ensembl(GRCz11):ENSDARG00000014287 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23423 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eno2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH eno2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glycolytic process (more)
    Cellular Component phosphopyruvate hydratase complex (more)
    Molecular Function magnesium ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript eno2-202 (1)    Ensembl 698
    mRNA eno2-201 (1)    Ensembl 2328
    ncRNA eno2-002 (1)    Ensembl 552
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM eno2
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(eno2:Cerulean) eno2 Cerulean Danio rerio 1 3
    Tg(eno2:EGFP) eno2 EGFP Danio rerio 5 6
    Tg(eno2:Hsa.MAPT) eno2 Danio rerioHomo sapiens 1 2
    Tg(eno2:mRFP) eno2 mRFP Danio rerio 1 4
    tg2(eno2:cerulean) eno2 Cerulean Danio rerio 1 1
    Tg5(eno2:GCaMP3.5) eno2 GCaMP Danio rerio 1 3
    MARKER RELATIONSHIPS
    eno2 Contained in: [BAC] CH211-51M24 (1), DKEY-89B17 (1) (order this)
    eno2 Encodes: [EST] fc09h05, IMAGE:6911542 (1)
    [cDNA] MGC:92418 (1), MGC:191187 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003848 (1) 1379 nt
    Genomic GenBank:AL772314 (1) 185640 nt
    Select Tool
    Polypeptide UniProtKB:Q6GQM9 (1) 434 aa
    Sequence Information (all 22)
    ORTHOLOGY for eno2 ( Chr: 19 )
    CITATIONS (36)