ZFIN ID: ZDB-GENE-040704-11
Gene Name: nuclear receptor subfamily 4, group A, member 1
Gene Symbol: nr4a1    Nomenclature History

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Attributions

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Previous Names: NGFIB (1), zgc:92434

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have RNA polymerase II proximal promoter sequence-specific DNA binding activity and glucocorticoid receptor binding activity. Predicted to be involved in cellular response to corticotropin-releasing hormone stimulus. Predicted to localize to the nucleus and transcription factor complex. Is expressed in axis; myotome; nervous system; and pectoral fin. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1).
Genome Resources: Alliance (1),  Gene:431720 (1),  Ensembl(GRCz11):ENSDARG00000000796 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-nr4a1
1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH nr4a1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH nr4a1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR003070 Orphan nuclear receptor
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA nr4a1-201 (1)    Ensembl 2945
nr4a1-202 (1)    Ensembl 784
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
SignaFish
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM nr4a1 No data available
MARKER RELATIONSHIPS
nr4a1 Contained in: [BAC] DKEY-197C14 (1) (order this)
nr4a1 Encodes: [EST] bc074092 (1), IMAGE:7162027 (1)
[cDNA] MGC:92434 (1), MGC:191871 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001002173 (1) 2950 nt
Genomic GenBank:CU469363 (1) 139797 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IC41 (1) 605 aa
Sequence Information (all 20)
ORTHOLOGY for nr4a1 ( Chr: 23 )
CITATIONS (33)