ZFIN ID: ZDB-GENE-040630-5
Gene Name: nuclear factor, erythroid 2-like 1a
Gene Symbol: nfe2l1a    Nomenclature History

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Previous Names: nfe2l1, nrf1a (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to localize to the cytoplasm and nucleus. Orthologous to human NFE2L1 (nuclear factor, erythroid 2 like 1).
Genome Resources: Alliance (1),  Gene:405781 (1),  Ensembl(GRCz11):ENSDARG00000030616 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu614]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015139Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26053 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-nfe2l1a N/A 3
    DISEASE ASSOCIATED WITH nfe2l1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nfe2l1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to oxidative stress (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR004826 Basic leucine zipper domain, Maf-type
    Domain IPR004827 Basic-leucine zipper domain
    Homologous_superfamily IPR008917 Transcription factor, Skn-1-like, DNA-binding domain superfamily
    Family IPR029847 Endoplasmic reticulum membrane sensor NFE2L1
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nfe2l1a-201 (1)    Ensembl 3303
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nfe2l1a No data available
    MARKER RELATIONSHIPS
    nfe2l1a Contained in: [BAC] CH211-246I5 (1)
    nfe2l1a Encodes: [EST] eu614 (1)
    [cDNA] MGC:193623 (1), MGC:193631 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212855 (1) 3299 bp
    Genomic GenBank:CR450718 (1) 151291 bp
    Select Tool
    Polypeptide UniProtKB:B3DGS0 (1) 707 aa
    Sequence Information (all 24)
    ORTHOLOGY for nfe2l1a ( Chr: 3 )
    CITATIONS (32)