ZFIN ID: ZDB-GENE-040630-1
Gene Name: GDNF family receptor alpha 2a
Gene Symbol: gfra2a    Nomenclature History

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Previous Name: gfra2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have signaling receptor activity. Involved in enteric nervous system development. Predicted to localize to external side of plasma membrane and receptor complex. Is expressed in brain; cranial ganglion; and enteric nervous system. Orthologous to human GFRA2 (GDNF family receptor alpha 2).
Genome Resources: Alliance (1),  Gene:405794 (1),  Ensembl(GRCz11):ENSDARG00000042723 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6102 Point Mutation Unknown Premature Stop ENU
sa10192 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sdu30Tg Transgenic Insertion Unknown Unknown DNA
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gfra2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gfra2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process enteric nervous system development (more)
    Cellular Component anchored component of membrane (more)
    Molecular Function signaling receptor activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gfra2a-201 (1)    Ensembl 1488
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gfra2a No data available
    MARKER RELATIONSHIPS
    gfra2a Contained in: [BAC] CH211-252D21 (1), DKEY-12I16 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001017996 (1)
    Genomic GenBank:BX470105 (1) 155300 nt
    Select Tool
    Polypeptide UniProtKB:B0S6A6 (1) 495 aa
    Sequence Information (all 11)
    ORTHOLOGY for gfra2a ( Chr: 8 )
    CITATIONS (20)