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ZIRC
ZFIN ID: ZDB-GENE-040629-4
Gene Name: RUNX family transcription factor 2b
Gene Symbol: runx2b
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits DNA-binding transcription factor activity and vitamin D receptor binding activity. Involved in chondrocyte differentiation; dorsal/ventral pattern formation; and positive regulation of  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14504 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25144 Point Mutation Unknown Premature Stop ENU
    sa32315 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH runx2b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cleidocranial dysplasia Cleidocranial dysplasia 119600
    Cleidocranial dysplasia, forme fruste, dental anomalies only 119600
    Cleidocranial dysplasia, forme fruste, with brachydactyly 119600
    Metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly 156510
    DISEASE ASSOCIATED WITH runx2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA-binding transcription factor activity (more)
    GO Terms (all 15)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA runx2b-201 (1) 1707
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM runx2b No data available
    MARKER RELATIONSHIPS
    runx2bContained in: [BAC] CH73-252E7 (1) (order this), DKEY-96J11 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212862 (1) 1759bp
    Genomic GenBank:BX510352 (1) 152387bp
    Select Tool
    Polypeptide UniProtKB:F1QB94 (1) 478aa
    Sequence Clusters UniGene:30423 (1)
    Sequence Information (all 33)
    ORTHOLOGY for runx2b (Chr: 20)
    CITATIONS (96)