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ZIRC
ZFIN ID: ZDB-GENE-040629-3
Gene Name: RUNX family transcription factor 2a
Gene Symbol: runx2a
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in hemopoiesis and neuron differentiation. Predicted to localize to the nucleus.  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2928 Point Mutation Unknown Splice Site ENU
sa13625 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH runx2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cleidocranial dysplasia Cleidocranial dysplasia 119600
    Cleidocranial dysplasia, forme fruste, dental anomalies only 119600
    Cleidocranial dysplasia, forme fruste, with brachydactyly 119600
    Metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly 156510
    DISEASE ASSOCIATED WITH runx2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA-binding transcription factor activity (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA runx2a-201 (1) 1650
    runx2a-202 (1) 1498
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM runx2a
    MARKER RELATIONSHIPS
    runx2aContained in: [BAC] CH211-34C18 (1) (order this), CH211-42B22 (1) (order this), CH211-253F14 (1) (order this)
    runx2aEncodes: [EST] eu739 (1)
    [cDNA] MGC:195229 (1) (order this), MGC:195237 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212858 (1) 1650bp
    Genomic GenBank:BX510331 (1) 150762bp
    Select Tool
    Polypeptide UniProtKB:B3DKD9 (1) 467aa
    Sequence Clusters UniGene:89714 (1)
    Sequence Information (all 42)
    ORTHOLOGY for runx2a (Chr: 17)
    CITATIONS (77)