ZFIN ID: ZDB-GENE-040629-2
Gene Name: Sp7 transcription factor
Gene Symbol: sp7
Sequence Ontology ID : SO:0000704

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Previous Names: osterix (2), osx (1)

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 35 figures from 26 publications
Directly Submitted Expression Data: 6 figures (29 images) from Thisse et al., 2005 [eu605]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
  anatomical structure, branchiostegal ray, branchiostegal ray osteoblast, branchiostegal ray 3 (all 47) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu2790 Point Mutation Unknown Premature Stop ENU
sa11475 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40813 Point Mutation Unknown Premature Stop ENU
    sus011 Small Deletion Exon 2 Unknown TALEN
    Targeting reagents: TALEN1-sp7 (1)
    PHENOTYPE
    Data: 8 figures from Kague et al., 2016
    Observed in: bone development, bone element, caudal fin lepidotrichium, ceratobranchial 5 primary tooth tooth mineralization (all 33) expand
    DISEASE ASSOCIATED WITH sp7 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    osteogenesis imperfecta type 12 ?Osteogenesis imperfecta, type XII 613849
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cranial suture morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013087 (1)
  • InterPro:IPR036236 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000054853 (1) 5629
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sp7
    Tg(sp7:EGFP), tg(sp7:gal4-vp16-2a-mcherry), tg(sp7:gal4-vp16-dnhsa.tead2-2a-mcherry), tg(sp7:mcherry), Tg(sp7:TETAM2-2A-Cerulean)
    MARKER RELATIONSHIPS
    sp7Contained in: [BAC] CH73-33G19 (1) (order this), CH211-158N11 (1) (order this)
    sp7Encodes: [EST] eu605 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212863 (1) 1433bp
    Genomic GenBank:CU929258 (1) 179511bp
    Select Tool
    Polypeptide UniProtKB:F6P1R7 (1) 528aa
    Sequence Clusters UniGene:90855 (1)
    Sequence Information (all 12)
    OTHER sp7 GENE PAGES
  • Alliance (1)
  • Gene:405789 (1)
  • VEGA:OTTDARG00000038290 (1)
  • Ensembl(GRCz10):ENSDARG00000019516 (1)
  • ORTHOLOGY for sp7 (Chr: 6)
    CITATIONS (72)