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General Information
ZIRC
ZFIN ID: ZDB-GENE-040625-79
Gene Name: solute carrier family 25 member 11
Gene Symbol: slc25a11    Nomenclature History

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Previous Names: fa07h09, wu:fa07h09, zgc:86898

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have oxoglutarate:malate antiporter activity. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in paraganglioma. Orthologous to human SLC25A11 (solute carrier family 25 member 11).
Genome Resources: Alliance (1),  Gene:415189 (1),  Ensembl(GRCz11):ENSDARG00000035741 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6904942]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015775Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH slc25a11 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Paragangliomas 6 618464
    DISEASE ASSOCIATED WITH slc25a11 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    Molecular Function oxoglutarate:malate antiporter activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR018108 (1)
  • InterPro:IPR023395 (1)
  • PROSITE:PS50920 (1)
  • Pfam:PF00153 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript slc25a11-202 (1)    Ensembl 790
    mRNA slc25a11-201 (1)    Ensembl 1667
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc25a11 No data available
    MARKER RELATIONSHIPS
    slc25a11 Contained in: [Fosmid] CH1073-264F11 (1) (order this)
    slc25a11 Encodes: [EST] fa07h09, IMAGE:6904942 (1) (order this)
    [cDNA] MGC:86898 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002099 (1) 1697 bp
    Genomic GenBank:CU656043 (1) 39383 bp
    Select Tool
    Polypeptide UniProtKB:F1R319 (1) 308 aa
    Sequence Clusters UniGene:661 (1)
    Sequence Information (all 15)
    ORTHOLOGY for slc25a11 ( Chr: 5 )
    CITATIONS (24)