ZFIN ID: ZDB-GENE-040625-7
Gene Name: aldo-keto reductase family 1, member B1 (aldose reductase)
Gene Symbol: akr1b1

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Previous Name: zgc:86611 (1)

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu329]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16601 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH akr1b1 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cellular_component (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001395 (1)
  • InterPro:IPR018170 (1)
  • InterPro:IPR020471 (1)
  • InterPro:IPR023210 (1)
  • PROSITE:PS00062 (1)
  • PROSITE:PS00063 (1)
  • PROSITE:PS00798 (1)
  • Pfam:PF00248 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA akr1b1-001 (1) 1293
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM akr1b1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    akr1b1Contained in: [BAC] DKEY-14K9 (1) (order this), DKEY-180P18 (1) (order this)
    akr1b1Encodes: [EST] eu329 (1)
    [cDNA] MGC:86611 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002048 (1) 1187bp
    Genomic GenBank:BX571796 (1) 130699bp
    Select Tool
    Polypeptide UniProtKB:Q5TYY5 (1) 315aa
    Sequence Clusters UniGene:88645 (1)
    Sequence Information (all 13)
    OTHER akr1b1 GENE PAGES
  • Gene:415138 (1)
  • VEGA:OTTDARG00000007893 (1)
  • Ensembl(GRCz10):ENSDARG00000006215 (1)
  • ORTHOLOGY for akr1b1 (Chr: 4)
    Species Symbol Chromosome Accession # Evidence
    Human AKR1B1 7
  • Gene:231
  • OMIM:103880
  • HGNC:381
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (16)