Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040625-7
Gene Name: aldo-keto reductase family 1, member B1 (aldose reductase)
Gene Symbol: akr1b1
Previous Name: zgc:86611 (1)
Location: Chr: 4   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu329]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa16601
PHENOTYPE No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component cellular_component (more)
Molecular Function oxidoreductase activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001395 (1)
  • InterPro:IPR018170 (1)
  • InterPro:IPR020471 (1)
  • InterPro:IPR023210 (1)
  • PROSITE:PS00062 (1)
  • PROSITE:PS00063 (1)
  • PROSITE:PS00798 (1)
  • Pfam:PF00248 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA akr1b1-001 (1) 1293
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM akr1b1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    akr1b1 Contained in: [BAC] DKEY-14K9 (1), DKEY-180P18 (1)
    akr1b1 Encodes: [EST] eu329 (1)
    [cDNA] MGC:86611 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002048 (1) 1187 bp
    Genomic GenBank:BX571796 (1) 130699 bp
    Select Tool
    Polypeptide UniProtKB:Q5TYY5 (1) 315 aa
    Sequence Clusters UniGene:88645 (1)
    Sequence Information (all 13)
    OTHER akr1b1 GENE PAGES
  • Gene:415138 (1)
  • VEGA:OTTDARG00000007893 (1)
  • Ensembl(Zv9):ENSDARG00000006215 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish akr1b1 4  
    Human AKR1B1 7 (7q35)
  • OMIM:103880
  • Gene:231
  • Orthology Details
    CITATIONS (15)