Gene

psmc1b

ID

ZDB-GENE-040625-69

Name

proteasome 26S subunit, ATPase 1b

Symbol

psmc1b Nomenclature History

Previous Names

wu:fj14c10 (1)
zgc:86923

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have TBP-class protein binding activity and proteasome-activating ATPase activity. Predicted to be involved in protein catabolic process. Predicted to localize to proteasome regulatory particle, base subcomplex. Orthologous to human PSMC1 (proteasome 26S subunit, ATPase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Link et al., 2006

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With psmc1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
neurodevelopmental disorder with poor growth, spastic tetraplegia, and hearing loss	Alliance	?Neurodevelopmental disorder with poor growth, spastic tetraplegia, and hearing loss	620071

Associated With psmc1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003960	ATPase, AAA-type, conserved site
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Domain	IPR032501	Proteasomal ATPase OB C-terminal domain
Domain	IPR041569	AAA ATPase, AAA+ lid domain
Family	IPR005937	26S proteasome regulatory subunit P45-like
Family	IPR035244	26S Proteasome regulatory subunit 4
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase