Gene

idh3b

ID
ZDB-GENE-040625-174
Name
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
Symbol
idh3b Nomenclature History
Previous Names
  • zgc:86647
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have isocitrate dehydrogenase (NAD+) activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to localize to mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; optic tectum; and pronephric duct. Human ortholog(s) of this gene implicated in retinitis pigmentosa 46. Orthologous to human IDH3B (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With idh3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 46 Alliance Retinitis pigmentosa 46 612572
Associated With idh3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site
Domain IPR024084 Isopropylmalate dehydrogenase-like domain
Family IPR004434 Isocitrate dehydrogenase NAD-dependent
Domain Details Per Protein
Protein Length Isocitrate dehydrogenase NAD-dependent Isocitrate/isopropylmalate dehydrogenase, conserved site Isopropylmalate dehydrogenase-like domain
UniProtKB:Q6IQR5 382
UniProtKB:A0A2R8QPC9 386
UniProtKB:A0A2R8PY75 383
UniProtKB:F8W2V6 383
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations