ZFIN ID: ZDB-GENE-040625-167
Gene Name: RAP1A, member of RAS oncogene family a
Gene Symbol: rap1aa    Nomenclature History

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Previous Names: rap1a, Rap1b (1), wu:fc66g06 (1), zgc:86676

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Exhibits MAP kinase kinase activity. Involved in chondrocyte intercalation involved in growth plate cartilage morphogenesis and heart development. Predicted to localize to the plasma membrane. Orthologous to human RAP1A (RAP1A, member of RAS oncogene family).
Genome Resources: Alliance (1),  Gene:415242 (1),  Ensembl(GRCz11):ENSDARG00000012553 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6911289]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-rap1aa N/A 3
PHENOTYPE
Data: text only from Tsai et al., 2007
Observed in:
DISEASE ASSOCIATED WITH rap1aa HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH rap1aa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cartilage morphogenesis (more)
Cellular Component membrane (more)
Molecular Function MAP kinase kinase activity (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR005225 Small GTP-binding protein domain
Family IPR001806 Small GTPase
Family IPR020849 Small GTPase superfamily, Ras-type
Family IPR038851 Ras-related protein Rap1
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rap1aa-201 (1)    Ensembl 1744
rap1aa-202 (1)    Ensembl 1740
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM rap1aa No data available
MARKER RELATIONSHIPS
rap1aa Contained in: [BAC] DKEY-193L3 (1) (order this)
rap1aa Encodes: [EST] fc66g06, IMAGE:6911289 (1)
[cDNA] MGC:86676 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001002152 (1) 1778 nt
Genomic GenBank:BX664742 (1) 215608 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q6IQP4 (1) 185 aa
Sequence Information (all 15)
ORTHOLOGY for rap1aa ( Chr: 8 )
CITATIONS (25)