ZFIN ID: ZDB-GENE-040625-1
Gene Name: gremlin 1a, DAN family BMP antagonist
Gene Symbol: grem1a    Nomenclature History

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Previous Names: grem1, zgc:136702

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have BMP binding activity and receptor ligand activity. Predicted to be involved in animal organ morphogenesis and sequestering of BMP from receptor via BMP binding activity. Predicted to localize to extracellular space. Is expressed in several structures, including cranial vault; notochord; pectoral fin bud; pronephric duct; and segmental plate. Orthologous to human GREM1 (gremlin 1, DAN family BMP antagonist).
Genome Resources: Alliance (1), 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH grem1a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH grem1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process animal organ morphogenesis (more)
Cellular Component extracellular region (more)
Molecular Function cytokine activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA grem1a-201 (1)    Ensembl 1297
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM grem1a No data available
MARKER RELATIONSHIPS
grem1a Contained in: [BAC] DKEY-81B15 (1) (order this)
grem1a Encodes: [cDNA] MGC:136702 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA GenBank:BC115232 (1) 1320 nt
Genomic GenBank:BX248136 (1) 222316 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q6T937 (1) 177 aa
Sequence Information (all 6)
ORTHOLOGY for grem1a ( Chr: 20 )
CITATIONS (22)