Gene

pth1b

ID
ZDB-GENE-040623-2
Name
parathyroid hormone 1b
Symbol
pth1b Nomenclature History
Previous Names
  • pth2 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits hormone activity. Predicted to be involved in cellular calcium ion homeostasis. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in several diseases, including chronic kidney disease; diabetes mellitus (multiple); familial isolated hypoparathyroidism; hyperphosphatemia; and secondary hyperparathyroidism. Is expressed in heart; immune system; integument; muscle; and nervous system. Orthologous to human PTH (parathyroid hormone).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pth1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial isolated hypoparathyroidism Alliance Hypoparathyroidism, familial isolated 1 146200
hypoparathyroidism Alliance Hypoparathyroidism, familial isolated 1 146200
Associated With pth1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001415 Parathyroid hormone/parathyroid hormone-related protein
Family IPR003625 Parathyroid hormone
Domain Details Per Protein
Protein Length Parathyroid hormone Parathyroid hormone/parathyroid hormone-related protein
UniProtKB:Q6WQ24 99
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations