Gene
gnpat
- ID
- ZDB-GENE-040618-4
- Name
- glyceronephosphate O-acyltransferase
- Symbol
- gnpat Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable glycerol-3-phosphate O-acyltransferase activity and glycerone-phosphate O-acyltransferase activity. Predicted to be involved in several processes, including ether lipid biosynthetic process; phospholipid biosynthetic process; and triglyceride biosynthetic process. Predicted to act upstream of or within cellular lipid metabolic process. Predicted to be active in mitochondrial membrane and peroxisomal membrane. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata type 2. Orthologous to human GNPAT (glyceronephosphate O-acyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| rhizomelic chondrodysplasia punctata type 2 | Alliance | Rhizomelic chondrodysplasia punctata, type 2 | 222765 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase | GPAT/DHAPAT, acyltransferase domain | GPAT/DHAPAT, C-terminal domain | Phospholipid/glycerol acyltransferase |
|---|---|---|---|---|---|
|
UniProtKB:F1QAU7
|
668 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available