ZFIN ID: ZDB-GENE-040611-2
Gene Name: neuropilin 2a
Gene Symbol: nrp2a    Nomenclature History

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Previous Name: npn-2A (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Exhibits identical protein binding activity. Involved in neural crest cell migration; regulation of vascular endothelial growth factor receptor signaling pathway; and vasculogenesis. Predicted to localize to integral component of membrane. Is expressed in axial vasculature; cranial neural crest cell; fin bud; and nervous system. Orthologous to human NRP2 (neuropilin 2).
Genome Resources: Alliance (1),  Gene:405901 (1),  Ensembl(GRCz11):ENSDARG00000096546 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021215Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13255 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13721 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25512 Point Mutation Unknown Splice Site ENU
    sa30798 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32581 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko100a Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko100b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-nrp2a 1
    CRISPR2-nrp2a
    1
    CRISPR3-nrp2a
    1
    CRISPR4-nrp2a
    1
    CRISPR5-nrp2a
    1
    MO1-nrp2a N/A 3
    MO2-nrp2a N/A 3
    MO3-nrp2a N/A 2
    MO4-nrp2a N/A 1
    DISEASE ASSOCIATED WITH nrp2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nrp2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neural crest cell migration (more)
    Cellular Component integral component of membrane (more)
    Molecular Function identical protein binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nrp2a-201 (1)    Ensembl 5278
    nrp2a-202 (1)    Ensembl 410
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nrp2a No data available
    MARKER RELATIONSHIPS
    nrp2a Contained in: [BAC] CH73-76B22 (1)
    [Fosmid] CH1073-331F6 (1), CH1073-435A3 (1)
    nrp2a Encodes: [cDNA] MGC:193601 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212965 (1) 5316 nt
    Genomic GenBank:CU469569 (1) 102276 nt
    Select Tool
    Polypeptide UniProtKB:B3DFP6 (1) 927 aa
    Sequence Information (all 35)
    ORTHOLOGY for nrp2a ( Chr: 1 )
    CITATIONS (49)