ZFIN ID: ZDB-GENE-040526-1
Gene Name: DAZ interacting zinc finger protein 1
Gene Symbol: dzip1    Nomenclature History

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Previous Names: igu, iguana, si:dz52i16.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in several processes, including circulatory system development; nervous system development; and regulation of signal transduction. Localizes to several cellular components, including the ciliary basal body; non-motile cilium; and nucleus. Orthologous to human DZIP1 (DAZ interacting zinc finger protein 1).
Genome Resources: Alliance (1),  Gene:402875 (1),  Ensembl(GRCz11):ENSDARG00000000943 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu116]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fo10a Point Mutation Unknown Premature Stop
  • Zebrafish International Resource Center (ZIRC) (order this)
  • i33 Point Mutation Unknown Unknown ENU
    la025733Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025734Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025735Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa8922 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20624 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26672 Point Mutation Unknown Splice Site ENU
    tm79a Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ts294e Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dzip1 N/A 3
    MO2-dzip1 N/A 2
    MO3-dzip1 N/A 1
    MO4-dzip1 N/A 1
    MO5-dzip1 N/A 1
    DISEASE ASSOCIATED WITH dzip1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dzip1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process NLS-bearing protein import into nucleus (more)
    Cellular Component ciliary basal body (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR013087 Zinc finger C2H2-type
    Domain IPR032714 Zinc finger protein DZIP1, N-terminal
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dzip1-201 (1)    Ensembl 3260
    dzip1-204 (1)    Ensembl 3200
    ottdart00000003879 (1) 1612
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dzip1
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hsp70l:GFP-dzip1) hsp70l dzip1GFP Danio rerio 1 2
    MARKER RELATIONSHIPS
    dzip1 Contained in: [BAC] CH211-181L5 (1)
    [PAC] BUSM1-52I16, BUSM1-228E24
    dzip1 Encodes: [EST] eu116 (1)
    [cDNA] MGC:193730 (1), MGC:193744 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001501 (1) 3260 bp
    Genomic GenBank:AL591370 (1) 131033 bp
    Select Tool
    Polypeptide UniProtKB:Q7T019 (1) 898 aa
    Sequence Information (all 41)
    ORTHOLOGY for dzip1 ( Chr: 6 )
    CITATIONS (72)