ZFIN ID: ZDB-GENE-040516-3
Gene Name: protein phosphatase 1, catalytic subunit, alpha isozyme a
Gene Symbol: ppp1caa    Nomenclature History

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Previous Names: ppp1ca, PPP1CAa (1), wu:fc04c08, wu:fc09b07, wu:fc30g11, wu:fe05h08, zgc:85729

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine phosphatase activity. Involved in convergent extension. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; digestive system; eye; otic vesicle; and pectoral fin. Orthologous to human PPP1CA (protein phosphatase 1 catalytic subunit alpha).
Genome Resources: Alliance (1),  Gene:407980 (1),  Ensembl(GRCz11):ENSDARG00000003486 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:85729]
  4 figures (12 images) from Rauch et al., 2003 [fq34g11]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8688 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26083 Point Mutation Unknown Premature Stop ENU
    sa40087 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ppp1caa N/A 1
    PHENOTYPE
    Data: Fig. 6 from Shimizu et al., 2014
    Observed in:
    DISEASE ASSOCIATED WITH ppp1caa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppp1caa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process convergent extension (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ppp1caa-201 (1)    Ensembl 4544
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ppp1caa No data available
    MARKER RELATIONSHIPS
    ppp1caa Contained in: [BAC] DKEY-105I19 (1) (order this)
    ppp1caa Encodes: [EST] fc04c08, fc09b07, fc30g11, fe05h08, fq34g11 (1) (order this)
    [cDNA] MGC:85729 (1), MGC:173884 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_214811 (1) 2224 nt
    Genomic GenBank:BX682556 (1) 244555 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6NSN6 (1) 331 aa
    Sequence Information (all 24)
    ORTHOLOGY for ppp1caa ( Chr: 3 )
    CITATIONS (25)