Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040516-14
Gene Name: rho/rac guanine nucleotide exchange factor (GEF) 18a
Gene Symbol: arhgef18a
Previous Names: arhgef18, wu:fc21e04, wu:fj05f11, zgc:85686
Location: Chr: 2   Details
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la023658Tg, sa16319, sa19819
PHENOTYPE No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of Rho protein signal transduction (more)
Molecular Function Rho guanyl-nucleotide exchange factor activity (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR015721 (1)
  • PROSITE:PS50003 (1)
  • PROSITE:PS50010 (1)
  • Pfam:PF00621 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA arhgef18a-001 (1) 4184
    arhgef18a-002 (1) 554
    arhgef18a-003 (1) 389
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef18a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    arhgef18a Contained in: [BAC] DKEY-57K2 (1)
    arhgef18a Encodes: [EST] fc21e04 (1), fj05f11 (1)
    [cDNA] MGC:85686 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_214818 (1) 4242 bp
    Genomic GenBank:BX539340 (1) 234470 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1REH9 (1) 940 aa
    Sequence Clusters UniGene:32570 (1)
    Sequence Information (all 19)
    OTHER arhgef18a GENE PAGES
  • Gene:407987 (1)
  • VEGA:OTTDARG00000019938 (1)
  • Ensembl(Zv9):ENSDARG00000011157 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish arhgef18a 2  
    Human ARHGEF18 19 (19p13.3)
  • Gene:23370
  • Mouse Arhgef18 8 ( 1.92 cM)
  • MGI:2142567
  • Gene:102098
  • Orthology Details
    CITATIONS (18)