ZFIN ID: ZDB-GENE-040516-14
Gene Name: rho/rac guanine nucleotide exchange factor (GEF) 18a
Gene Symbol: arhgef18a
Previous Names: arhgef18, wu:fc21e04, wu:fj05f11, zgc:85686
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la023658Tg Transgenic Insertion DNA
sa16319 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa19819 Point Mutation ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH arhgef18a HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process regulation of Rho protein signal transduction (more)
    Molecular Function Rho guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR011993 (1)
  • PROSITE:PS50003 (1)
  • PROSITE:PS50010 (1)
  • Pfam:PF00621 (1)
  • Pfam:PF16652 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA arhgef18a-001 (1) 4184
    arhgef18a-002 (1) 554
    arhgef18a-003 (1) 389
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef18a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    arhgef18aContained in: [BAC] DKEY-57K2 (1) (order this)
    arhgef18aEncodes: [EST] fc21e04 (1), fj05f11 (1)
    [cDNA] MGC:85686 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_214818 (1) 4242bp
    Genomic GenBank:BX539340 (1) 234470bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1REH9 (1) 940aa
    Sequence Clusters UniGene:32570 (1)
    Sequence Information (all 19)
    OTHER arhgef18a GENE PAGES 
  • Gene:407987 (1)
  • VEGA:OTTDARG00000019938 (1)
  • Ensembl(GRCz10):ENSDARG00000011157 (1)
  • ORTHOLOGY for arhgef18a (Chr: 2) 
    Species Symbol Chromosome Accession # Evidence
    Human ARHGEF18 19
  • Gene:23370
  • OMIM:616432
  • HGNC:17090
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Arhgef18 8
  • MGI:2142567
  • Gene:102098
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (18)