ZFIN ID: ZDB-GENE-040513-5
Gene Name: acid-sensing (proton-gated) ion channel family member 4a
Gene Symbol: asic4a    Nomenclature History

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Previous Names: accn4a, zASIC4.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Exhibits ligand-gated sodium channel activity. Predicted to be involved in sodium ion transport. Localizes to the integral component of plasma membrane. Is expressed in gill; retinal ganglion cell layer; and retinal photoreceptor layer. Orthologous to human ASIC4 (acid sensing ion channel subunit family member 4).
Genome Resources: Alliance (1),  Gene:407668 (1),  Ensembl(GRCz11):ENSDARG00000025162 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7173 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH asic4a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH asic4a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process ion transport (more)
Cellular Component integral component of plasma membrane (more)
Molecular Function ligand-gated sodium channel activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR001873 Epithelial sodium channel
Conserved_site IPR020903 Epithelial sodium channel, conserved site
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA asic4a-202 (1)    Ensembl 1446
asic4a-203 (1)    Ensembl 813
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM asic4a No data available
MARKER RELATIONSHIPS
asic4a Contained in: [BAC] DKEY-22P6 (1) (order this), DKEY-31N3 (1) (order this), DKEY-244H12 (1) (order this)
[Fosmid] CH1073-64G16 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_214787 (1) 2286 bp
Genomic GenBank:CU570898 (1) 158863 bp
Select Tool
Polypeptide UniProtKB:F1QRF3 (1) 539 aa
Sequence Clusters UniGene:91508 (1)
Sequence Information (all 17)
ORTHOLOGY for asic4a ( Chr: 9 )
CITATIONS (22)