ZFIN ID: ZDB-GENE-040513-2
Gene Name: acid-sensing (proton-gated) ion channel 1a
Gene Symbol: asic1a    Nomenclature History

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Previous Names: zASIC1.2 (1), accn2b

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Exhibits ligand-gated sodium channel activity. Predicted to be involved in cellular response to pH and protein homotrimerization. Localizes to integral component of plasma membrane. Is expressed in brain; eye; and gill. Orthologous to human ASIC1 (acid sensing ion channel subunit 1).
Genome Resources: Alliance (1),  Gene:791696 (1),  Ensembl(GRCz11):ENSDARG00000008329 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14670 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21190 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH asic1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH asic1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to pH (more)
    Cellular Component integral component of plasma membrane (more)
    Molecular Function ligand-gated sodium channel activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA asic1a-201 (1)    Ensembl 3385
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM asic1a No data available
    MARKER RELATIONSHIPS
    asic1a Contained in: [BAC] CH211-255G12 (1)
    asic1a Encodes: [cDNA] MGC:193950 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_214790 (1) 2800 nt
    Genomic GenBank:AL954310 (1) 156407 nt
    Select Tool
    Polypeptide UniProtKB:B0R1B0 (1) 501 aa
    Sequence Information (all 15)
    ORTHOLOGY for asic1a ( Chr: 8 )
    CITATIONS (24)