ZFIN ID: ZDB-GENE-040428-2
Gene Name: actin related protein 3
Gene Symbol: actr3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to contribute to actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Predicted to localize to Arp2/3 protein complex and actin cortical patch. Human ortholog(s) of this gene implicated in opisthorchiasis. Orthologous to human ACTR3 (actin related protein 3).
Genome Resources: Alliance (1),  Gene:406250 (1),  Ensembl(GRCz11):ENSDARG00000091138 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:111789]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34799 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-actr3 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH actr3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH actr3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament organization (more)
    Cellular Component Arp2/3 protein complex (more)
    Molecular Function ATP binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM actr3 No data available
    MARKER RELATIONSHIPS
    actr3 Encodes: [cDNA] MGC:111789 (1), MGC:191678 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003944 (1) 1409 nt
    Genomic GenBank:CABZ01079476 (1)
    Polypeptide UniProtKB:Q6PUQ3 (1) 418 aa
    Sequence Information (all 21)
    ORTHOLOGY for actr3 ( Chr: 9 )
    CITATIONS (17)