ZFIN ID: ZDB-GENE-040426-993
Gene Name: nuclear receptor corepressor 1
Gene Symbol: ncor1    Nomenclature History

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Previous Names: NCOR (1), zgc:56355

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have several functions, including histone deacetylase binding activity; thyroid hormone receptor binding activity; and transcription corepressor activity. Involved in anterior/posterior pattern specification; hindbrain development; and neutrophil differentiation. Predicted to colocalize with Sin3 complex. Is expressed in several structures, including epidermis; head; liver; pleuroperitoneal region; and ventricular system. Orthologous to human NCOR1 (nuclear receptor corepressor 1).
Genome Resources: Alliance (1),  Gene:393246 (1),  Ensembl(GRCz11):ENSDARG00000035285 (1)
GENE EXPRESSION
All Expression Data: 13 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56355]
  7 figures (7 images) from Thisse et al., 2008 [MGC:56355]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025077Tg Transgenic Insertion Unknown Unknown DNA
sa2211 Point Mutation Unknown Splice Site ENU
sa13203 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13384 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17067 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17231 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18033 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20512 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38494 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38495 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38496 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40530 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40531 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ncor1 N/A 2
    MO2-ncor1 N/A 1
    DISEASE ASSOCIATED WITH ncor1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ncor1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anterior/posterior pattern specification (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ncor1-202 (1)    Ensembl 8232
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ncor1 No data available
    MARKER RELATIONSHIPS
    ncor1 Contained in: [BAC] CH211-202A12 (1), DKEY-65B12 (1) (order this)
    ncor1 Encodes: [cDNA] MGC:56355 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200276 (1) 9591 nt
    Genomic GenBank:AL953908 (1) 193129 nt
    Select Tool
    Polypeptide UniProtKB:A8B6H7 (1) 2409 aa
    Sequence Information (all 34)
    ORTHOLOGY for ncor1 ( Chr: 5 )
    CITATIONS (41)