ZFIN ID: ZDB-GENE-040426-984
Gene Name: protein kinase C and casein kinase substrate in neurons 3
Gene Symbol: pacsin3    Nomenclature History

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Previous Names: fa11d03, fj67e09, wu:fa11d03 (1), wu:fj67e09 (1), wu:fq16a06 (1), zgc:56324

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have cytoskeletal protein binding activity and phospholipid binding activity. Involved in notochord cell differentiation and notochord formation. Localizes to plasma membrane. Is expressed in several structures, including endoderm; epidermis; intestinal bulb primordium; sensory system; and ventricular zone. Orthologous to human PACSIN3 (protein kinase C and casein kinase substrate in neurons 3).
Genome Resources: Alliance (1),  Gene:393964 (1),  Ensembl(GRCz11):ENSDARG00000099339 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa41028 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pacsin3 N/A 1
    MO2-pacsin3 N/A 1
    DISEASE ASSOCIATED WITH pacsin3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pacsin3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process notochord cell differentiation (more)
    Cellular Component plasma membrane (more)
    Molecular Function cytoskeletal protein binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pacsin3-201 (1)    Ensembl 2581
    pacsin3-202 (1)    Ensembl 2629
    pacsin3-203 (1)    Ensembl 307
    pacsin3-204 (1)    Ensembl 283
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pacsin3 No data available
    MARKER RELATIONSHIPS
    pacsin3 Contained in: [BAC] CH73-359B13 (1), CH211-59B1 (1)
    pacsin3 Encodes: [EST] fa11d03, fj67e09, fq16a06 (1) (order this)
    [cDNA] MGC:56324 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200989 (1) 1622 nt
    Genomic GenBank:AL935050 (1) 177773 nt
    Select Tool
    Polypeptide UniProtKB:B0R118 (1) 435 aa
    Sequence Information (all 26)
    ORTHOLOGY for pacsin3 ( Chr: 7 )
    CITATIONS (21)