ZFIN ID: ZDB-GENE-040426-943
Gene Name: fragile X mental retardation, autosomal homolog 2
Gene Symbol: fxr2
Sequence Ontology ID : SO:0000704

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Previous Names: id:ibd5046, zgc:56215, zgc:77472

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have mRNA 3'-UTR binding activity, protein homodimerization activity, and translation regulator activity; predicted to be involved in negative regulation of translation, positive  ...
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2004 [MGC:56215]
  3 figures (4 images) from Kudoh et al., 2001 [ibd5046]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025883Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11430 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fxr2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fxr2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of translation (more)
    Cellular Component cytoplasm (more)
    Molecular Function mRNA binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004087 (1)
  • InterPro:IPR004088 (1)
  • InterPro:IPR008395 (1)
  • InterPro:IPR022034 (1)
  • InterPro:IPR032172 (1)
  • InterPro:IPR036612 (1)
  • InterPro:IPR040148 (1)
  • InterPro:IPR040472 (1)
  • PROSITE:PS51641 (1)
  • Pfam:PF00013 (1)
  • Pfam:PF05641 (1)
  • Pfam:PF12235 (1)
  • Pfam:PF16096 (1)
  • Pfam:PF17904 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fxr2-201 (1) 4106
    fxr2-202 (1) 2521
    fxr2-203 (1) 729
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fxr2 No data available
    MARKER RELATIONSHIPS
    fxr2Contained in: [BAC] DKEY-165A24 (1) (order this)
    fxr2Encodes: [EST] ibd5046 (order this)
    [cDNA] MGC:56215 (1) (order this), MGC:77472 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200211 (1) 3667bp
    Genomic GenBank:BX470211 (1) 173552bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8RJS5 (1) 680aa
    Sequence Clusters UniGene:132273 (1)
    Sequence Information (all 19)
    OTHER fxr2 GENE PAGES
  • Alliance (1)
  • Gene:393180 (1)
  • VEGA:OTTDARG00000020119 (1)
  • ORTHOLOGY for fxr2 (Chr: 7)
    CITATIONS (24)