Gene
fxr2
- ID
- ZDB-GENE-040426-943
- Name
- FMR1 autosomal homolog 2
- Symbol
- fxr2 Nomenclature History
- Previous Names
-
- id:ibd5046
- zgc:56215
- zgc:77472
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable mRNA 3'-UTR binding activity and translation regulator activity. Predicted to be involved in several processes, including mRNA transport; positive regulation of long-term neuronal synaptic plasticity; and post-transcriptional regulation of gene expression. Predicted to act upstream of or within regulation of translation. Predicted to be located in cytoplasmic ribonucleoprotein granule. Predicted to be active in cytoplasmic stress granule; neuron projection; and nucleus. Is expressed in mesoderm; musculature system; and somite. Orthologous to human FXR2 (FMR1 autosomal homolog 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56215 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004087 | K Homology domain |
| Domain | IPR004088 | K Homology domain, type 1 |
| Domain | IPR008395 | Agenet-like domain |
| Domain | IPR022034 | Fragile X messenger ribonucleoprotein 1-like, C-terminal core |
| Domain | IPR032172 | Fragile X-related protein 1, C-terminal region 1 |
| Domain | IPR040472 | Synaptic functional regulator FMRP, KH0 domain |
| Domain | IPR041560 | FMR1, tudor domain |
| Domain | IPR047420 | RNA-binding protein FXR2, second Tudor-like Agenet domain |
| Domain | IPR047421 | RNA-binding protein FXR2, first Tudor-like Agenet domain |
| Domain | IPR047422 | RNA-binding protein FXR2, first type I K homology domain |
| Domain | IPR047424 | RNA-binding protein FXR2, second type I K homology domain |
| Family | IPR040148 | Fragile X messenger ribonucleoprotein 1 |
| Homologous_superfamily | IPR036612 | K Homology domain, type 1 superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Agenet-like domain | FMR1, tudor domain | Fragile X messenger ribonucleoprotein 1 | Fragile X messenger ribonucleoprotein 1-like, C-terminal core | Fragile X-related protein 1, C-terminal region 1 | K Homology domain | K Homology domain, type 1 | K Homology domain, type 1 superfamily | RNA-binding protein FXR2, first Tudor-like Agenet domain | RNA-binding protein FXR2, first type I K homology domain | RNA-binding protein FXR2, second Tudor-like Agenet domain | RNA-binding protein FXR2, second type I K homology domain | Synaptic functional regulator FMRP, KH0 domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NY99 | InterPro | 676 |
Interactions and Pathways
No data available
Plasmids
No data available