| ZFIN ID: ZDB-GENE-040426-943 |
| Gene Name: | fragile X mental retardation, autosomal homolog 2 | |||||||||||||
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| Gene Symbol: | fxr2 Nomenclature History |
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Attributions
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| Previous Names: | id:ibd5046, zgc:56215, zgc:77472 | |||||||||||||
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| Gene Type: | protein_coding_gene | |||||||||||||
| Location: | Chr: 7 Mapping Details/Browsers | |||||||||||||
| Description: | Predicted to have mRNA 3'-UTR binding activity; protein homodimerization activity; and translation regulator activity. Predicted to be involved in several processes, including posttranscriptional regulation of gene expression; regulation of alternative mRNA splicing, via spliceosome; and regulation of filopodium assembly. Predicted to localize to several cellular components, including dendrite; polysome; and postsynaptic density. Is expressed in mesoderm; musculature system; and somite. Orthologous to human FXR2 (FMR1 autosomal homolog 2). | |||||||||||||
| Genome Resources: | Alliance (1), Gene:393180 (1), Ensembl(GRCz11):ENSDARG00000016260 (1) | |||||||||||||
| Directly Submitted Expression Data: | 6 figures (13 images) from Thisse et al., 2004 [MGC:56215] |
| 3 figures (4 images) from Kudoh et al., 2001 [ibd5046] | |
| Wild-type Stages, Structures: | Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h) |
| High Throughput Expression: | GEO (1) , Expression Atlas (1) |
MUTATIONS AND SEQUENCE TARGETING REAGENTS
| Allele | Type | Localization | Consequence | Mutagen | Suppliers |
|---|---|---|---|---|---|
| la025883Tg | Transgenic Insertion | Unknown | Unknown | DNA |
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| sa11430 | Point Mutation | Unknown | Splice Site | ENU |
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GENE ONTOLOGY
| Ontology | GO Term |
|---|---|
| Biological Process | regulation of translation (more) |
| Cellular Component | axon (more) |
| Molecular Function | mRNA binding (more) |
| Type | Name | Length (nt) | Analysis | |
|---|---|---|---|---|
| mRNA |
fxr2-201
(1)
|
4106 |
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fxr2-202
(1)
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2521 |
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fxr2-203
(1)
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729 |
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| Browsers: UCSC, NCBI, Ensembl, ZFIN |
INTERACTIONS AND PATHWAYS
ANTIBODIES
No data available
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM fxr2
No data available
MARKER RELATIONSHIPS
| fxr2 Contained in: | [BAC] DKEY-165A24 (1) (order this) |
| fxr2 Encodes: |
[EST]
ibd5046
[cDNA] MGC:56215 (1), MGC:77472 (1) |
SEQUENCE INFORMATION
| Type | Accession # | Length (nt/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_200211 (1) | 3667 nt |
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| Genomic | GenBank:BX470211 (1) | 173552 nt | |
| Polypeptide | UniProtKB:A0A2R8RJS5 (1) | 680 aa |
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ORTHOLOGY for fxr2 (
Chr:
7
)
CITATIONS (27)