ZFIN ID: ZDB-GENE-040426-943
Gene Name: fragile X mental retardation, autosomal homolog 2
Gene Symbol: fxr2    Nomenclature History

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Previous Names: id:ibd5046, zgc:56215, zgc:77472

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have mRNA 3'-UTR binding activity; protein homodimerization activity; and translation regulator activity. Predicted to be involved in several processes, including posttranscriptional regulation of gene expression; regulation of alternative mRNA splicing, via spliceosome; and regulation of filopodium assembly. Predicted to localize to several cellular components, including dendrite; polysome; and postsynaptic density. Is expressed in mesoderm; musculature system; and somite. Orthologous to human FXR2 (FMR1 autosomal homolog 2).
Genome Resources: Alliance (1),  Gene:393180 (1),  Ensembl(GRCz11):ENSDARG00000016260 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025883Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11430 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-fxr2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fxr2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fxr2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of translation (more)
    Cellular Component cytoplasm (more)
    Molecular Function mRNA binding (more)
    GO Terms (all 27)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fxr2-201 (1)    Ensembl 4106
    fxr2-202 (1)    Ensembl 2521
    fxr2-203 (1)    Ensembl 729
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fxr2 No data available
    MARKER RELATIONSHIPS
    fxr2 Contained in: [BAC] DKEY-165A24 (1) (order this)
    fxr2 Encodes: [EST] ibd5046
    [cDNA] MGC:56215 (1), MGC:77472 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200211 (1) 3667 nt
    Genomic GenBank:BX470211 (1) 173552 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8RJS5 (1) 680 aa
    Sequence Information (all 18)
    ORTHOLOGY for fxr2 ( Chr: 7 )
    CITATIONS (28)