ZFIN Gene: cct8

ZFIN ID: ZDB-GENE-040426-876

ZFIN ID: ZDB-GENE-040426-876

Gene Name:

chaperonin containing TCP1, subunit 8 (theta)

Gene Symbol:

cct8 Nomenclature History

Previous Names:

bdav (1), bette davis (1), fa22h09 (1), wu:fa22h09 (1), zgc:56059 (1)

Gene Type:

protein_coding_gene

Location:

Chr: 10 Mapping Details/Browsers

Description:

Predicted to have ATP binding activity and unfolded protein binding activity. Involved in behavioral response to nicotine. Predicted to localize to chaperonin-containing T-complex. Is expressed in brain. Orthologous to human CCT8 (chaperonin containing TCP1 subunit 8).

Genome Resources:

Alliance (1), Gene:394037 (1), Ensembl(GRCz11):ENSDARG00000008243 (2)

GENE EXPRESSION
All Expression Data:	2 figures from 2 publications
Directly Submitted Expression Data:	1 figure (1 image) from Thisse et al., 2004 [MGC:56059]
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
	brain unspecified whole organism
High Throughput Expression:	GEO (1) Expression Atlas (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
mn30Gt	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
sa34906	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa41662	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

PHENOTYPE

Data:	2 figures from 2 publications
Observed in:	behavioral response to nicotine myotome skeletal muscle cell skeletal muscle skeletal myofibril assembly skeletal muscle cell skeletal muscle myofibril

DISEASE ASSOCIATED WITH cct8 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH cct8 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	behavioral response to nicotine (more)
Cellular Component	cytoplasm (more)
Molecular Function	ATP binding (more)

GO Terms (all 7)

PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available

TRANSCRIPTS
Type	Name	Length (nt)	Analysis
mRNA	cct8-201 (1)	1927	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Browsers: UCSC, NCBI, Ensembl, ZFIN

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM cct8 No data available

MARKER RELATIONSHIPS

cct8 Contained in:	[BAC] DKEY-76A19 (1) (order this)
cct8 Encodes:	[EST] fa22h09 [cDNA] MGC:56059 (1), MGC:191834 (1)

SEQUENCE INFORMATION

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_201062 (1)	1993 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CT573197 (1)	146332 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A0R4IJT8 (1)	558 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 20)

ORTHOLOGY for cct8 ( Chr: 10 )

CITATIONS (31)

{{control.fieldName}} Edit

Attributions

Add new Alias

Attributions for Alias: {{control.newAlias}}

Delete Alias: