ZFIN ID: ZDB-GENE-040426-876
Gene Name: chaperonin containing TCP1, subunit 8 (theta)
Gene Symbol: cct8    Nomenclature History

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Previous Names: bdav (1), bette davis (1), fa22h09 (1), wu:fa22h09 (1), zgc:56059 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and unfolded protein binding activity. Involved in behavioral response to nicotine. Predicted to localize to chaperonin-containing T-complex. Is expressed in brain. Orthologous to human CCT8 (chaperonin containing TCP1 subunit 8).
Genome Resources: Alliance (1),  Gene:394037 (1),  Ensembl(GRCz11):ENSDARG00000008243 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56059]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
mn30Gt Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34906 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41662 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • DISEASE ASSOCIATED WITH cct8 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cct8 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process behavioral response to nicotine (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cct8-201 (1)    Ensembl 1927
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cct8 No data available
    MARKER RELATIONSHIPS
    cct8 Contained in: [BAC] DKEY-76A19 (1) (order this)
    cct8 Encodes: [EST] fa22h09
    [cDNA] MGC:56059 (1), MGC:191834 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201062 (1) 1993 nt
    Genomic GenBank:CT573197 (1) 146332 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IJT8 (1) 558 aa
    Sequence Information (all 20)
    ORTHOLOGY for cct8 ( Chr: 10 )
    CITATIONS (31)