ZFIN ID: ZDB-GENE-040426-874
Gene Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Gene Symbol: sdha
Sequence Ontology ID : SO:0000704

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Previous Names: im:7141001, zgc:56051

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have electron transfer activity and succinate dehydrogenase (ubiquinone) activity; predicted to be involved in carboxylic acid metabolic process, cellular respiration, and mitochondrial  ...
GENE EXPRESSION
All Expression Data: 14 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7141001]
  6 figures (11 images) from Thisse et al., 2004 [IMAGE:6897154]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23438 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36776 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sdha HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    dilated cardiomyopathy 1GG Cardiomyopathy, dilated, 1GG 613642
    Leigh disease Leigh syndrome 256000
    mitochondrial complex II deficiency Mitochondrial respiratory chain complex II deficiency 252011
    paraganglioma Paragangliomas 5 614165
    DISEASE ASSOCIATED WITH sdha VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process electron transport chain (more)
    Cellular Component mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) (more)
    Molecular Function succinate dehydrogenase (ubiquinone) activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003952 (1)
  • InterPro:IPR003953 (1)
  • InterPro:IPR011281 (1)
  • InterPro:IPR014006 (1)
  • InterPro:IPR015939 (1)
  • InterPro:IPR027477 (1)
  • InterPro:IPR036188 (1)
  • InterPro:IPR037099 (1)
  • PROSITE:PS00504 (1)
  • Pfam:PF00890 (1)
  • Pfam:PF02910 (1)
  • EC:1.3.5.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA sdha-003 (1) 806
    sdha-004 (1) 700
    sdha-005 (1) 752
    mRNA sdha-201 (1) 2543
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sdha No data available
    MARKER RELATIONSHIPS
    sdhaContained in: [BAC] CH73-216M24 (1) (order this), DKEYP-84F11 (1)
    sdhaEncodes: [EST] IMAGE:6897154 (1) (order this), IMAGE:7141001 (1) (order this)
    [cDNA] MGC:56051 (1) (order this), MGC:191735 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200910 (1) 2576bp
    Genomic GenBank:BX890617 182182bp
    Select Tool
    Polypeptide UniProtKB:Q6TNQ9 (1) 663aa
    Sequence Clusters UniGene:105233 (1)
    Sequence Information (all 22)
    OTHER sdha GENE PAGES
  • Alliance (1)
  • Gene:393884 (1)
  • VEGA:OTTDARG00000032328 (1)
  • Ensembl(GRCz11):ENSDARG00000016721 (2)
  • ORTHOLOGY for sdha (Chr: 19)
    CITATIONS (53)