Gene

wdr45b

ID
ZDB-GENE-040426-863
Name
WD repeat domain 45B
Symbol
wdr45b Nomenclature History
Previous Names
  • wdr45l
  • zgc:56002 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have phosphatidylinositol-3,5-bisphosphate binding activity and phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in several processes, including autophagy of mitochondrion; autophagy of nucleus; and protein localization to phagophore assembly site. Predicted to localize to several cellular components, including extrinsic component of membrane; lysosome; and phagophore assembly site membrane. Orthologous to human WDR45B (WD repeat domain 45B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wdr45b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures 617977
Associated With wdr45b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length WD40 repeat WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q7ZUW6 344
UniProtKB:A8KC31 344
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations