Gene
sepsecs
- ID
- ZDB-GENE-040426-859
- Name
- Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
- Symbol
- sepsecs Nomenclature History
- Previous Names
-
- sla/lpl
- zgc:55980
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have tRNA binding activity. Predicted to be involved in selenocysteine incorporation. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2D. Orthologous to human SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55980 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pontocerebellar hypoplasia type 2D | Alliance | Pontocerebellar hypoplasia type 2D | 613811 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | O-phosphoseryl-tRNA(Sec) selenium transferase | Pyridoxal phosphate-dependent transferase | Pyridoxal phosphate-dependent transferase, major domain | SepSecS/SepCysS family |
|---|---|---|---|---|---|
|
UniProtKB:Q803A7
|
490 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available