Gene

cdc5l

ID

ZDB-GENE-040426-821

Name

CDC5 cell division cycle 5-like (S. pombe)

Symbol

cdc5l Nomenclature History

Previous Names

zgc:55853

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within RNA splicing; cell division; and mRNA processing. Predicted to be located in nuclear speck. Predicted to be part of Prp19 complex and spliceosomal complex. Human ortholog(s) of this gene implicated in osteosarcoma. Orthologous to human CDC5L (cell division cycle 5 like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55853 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cdc5l Human Ortholog

No data available

Associated With cdc5l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001005	SANT/Myb domain
Domain	IPR017930	Myb domain
Domain	IPR021786	Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal
Domain	IPR047240	Pre-mRNA splicing factor component CDC5L/Cef1, second SANT/myb-like domain
Family	IPR047242	Pre-mRNA splicing factor component CDC5L/Cef1
Homologous_superfamily	IPR009057	Homedomain-like superfamily