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ZIRC
ZFIN ID: ZDB-GENE-040426-800
Gene Name: zw10 kinetochore protein
Gene Symbol: zw10    Nomenclature History

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Previous Name: zgc:55782 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and mitotic spindle assembly checkpoint. Predicted to localize to the RZZ complex. Orthologous to human ZW10 (zw10 kinetochore protein).
Genome Resources: Alliance (1),  Gene:393110 (1),  Ensembl(GRCz11):ENSDARG00000018738 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55782]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011689Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1742 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH zw10 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH zw10 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitotic cell cycle (more)
    Cellular Component chromosome, centromeric region (more)
    Molecular Function molecular_function (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR009361 (1)
  • Pfam:PF06248 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zw10-201 (1)    Ensembl 2666
    ncRNA zw10-002 (1) 745
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zw10 No data available
    MARKER RELATIONSHIPS
    zw10 Contained in: [BAC] DKEYP-14B8 (1)
    zw10 Encodes: [cDNA] MGC:55782 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200141 (1) 2670 bp
    Genomic GenBank:BX296544 (1) 168838 bp
    Select Tool
    Polypeptide UniProtKB:F1QYH5 (1) 771 aa
    Sequence Clusters UniGene:119861 (1)
    Sequence Information (all 10)
    ORTHOLOGY for zw10 ( Chr: 21 )
    CITATIONS (29)