ZFIN ID: ZDB-GENE-040426-784
Gene Name: abhydrolase domain containing 2, acylglycerol lipase a
Gene Symbol: abhd2a    Nomenclature History

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Previous Names: abhd2, zgc:55722

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have carboxylic ester hydrolase activity; hormone binding activity; and steroid hormone receptor activity. Predicted to be involved in several processes, including medium-chain fatty acid metabolic process; response to steroid hormone; and sperm capacitation. Predicted to localize to the sperm flagellum and sperm plasma membrane. Orthologous to human ABHD2 (abhydrolase domain containing 2).
Genome Resources: Alliance (1),  Gene:393888 (1),  Ensembl(GRCz11):ENSDARG00000025797 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55722]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31551 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abhd2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH abhd2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process acylglycerol catabolic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function acetylesterase activity (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000073 Alpha/beta hydrolase fold-1
    Family IPR012020 AB hydrolase 4 family
    Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abhd2a-201 (1)    Ensembl 1667
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abhd2a No data available
    MARKER RELATIONSHIPS
    abhd2a Encodes: [cDNA] MGC:55722 (1), MGC:192896 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200914 (1) 1662 nt
    Polypeptide UniProtKB:B2GT97 (1) 432 aa
    Sequence Information (all 14)
    ORTHOLOGY for abhd2a ( Chr: 7 )
    CITATIONS (21)