Gene

prkcsh

ID
ZDB-GENE-040426-770
Name
protein kinase C substrate 80K-H
Symbol
prkcsh Nomenclature History
Previous Names
  • zgc:55653
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and kinase activity. Involved in liver development and pronephros development. Predicted to localize to glucosidase II complex. Used to study polycystic liver disease. Human ortholog(s) of this gene implicated in liver disease and polycystic liver disease. Orthologous to human PRKCSH (protein kinase C substrate 80K-H).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkcsh Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
polycystic liver disease Alliance Polycystic liver disease 1 174050
Associated With prkcsh Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR002048 EF-hand domain
Domain IPR028146 Glucosidase II beta subunit, N-terminal
Domain IPR036607 Glucosidase 2 subunit beta-like
Family IPR039794 Glucosidase II beta subunit-like
Homologous_superfamily IPR009011 Mannose-6-phosphate receptor binding domain superfamily
Homologous_superfamily IPR036055 LDL receptor-like superfamily
Domain Details Per Protein
Protein Length EF-Hand 1, calcium-binding site EF-hand domain Glucosidase 2 subunit beta-like Glucosidase II beta subunit-like Glucosidase II beta subunit, N-terminal LDL receptor-like superfamily Mannose-6-phosphate receptor binding domain superfamily
UniProtKB:Q802Z2 529
UniProtKB:E9QBB3 232
UniProtKB:F1RBW3 529
UniProtKB:E9QHL2 248
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations