Gene

garem

ID

ZDB-GENE-040426-767

Name

GRB2 associated, regulator of MAPK1

Symbol

garem Nomenclature History

Previous Names

fam59a
zgc:55634

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have proline-rich region binding activity. Predicted to be involved in several processes, including cellular response to epidermal growth factor stimulus; epidermal growth factor receptor signaling pathway; and positive regulation of ERK1 and ERK2 cascade. Orthologous to human GAREM1 (GRB2 associated regulator of MAPK1 subtype 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:55634 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With garem Human Ortholog

No data available

Associated With garem Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR025946	CABIT domain
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily

Domain Details Per Protein

Protein	Length	CABIT domain	Sterile alpha motif/pointed domain superfamily
UniProtKB:Q7ZVU1 InterPro	867

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	garem-201 (1) Ensembl	Havana	5026 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations